Faculty: Kinsey

Portrait of Professor Steven Kinsey

Steven G. Kinsey

Ph.D.
Associate Professor
Director, Center for Advancement in Managing Pain

steven.kinsey@uconn.edu
P: (860) 486-8875
F: (860) 486-0001

University of Connecticut
School of Nursing
Storrs Hall, Room 112B
231 Glenbrook Road, Unit 4026
Storrs, Connecticut 06269

The Kinsey Lab Webpage

I am an educator and researcher with specialized training in pain, chronic disease, immunology, and pharmacology. My lab uses interdisciplinary tools, including pharmacological and genetic experimental animal models to study the opioid and endocannabinoid systems and how they control of pain, inflammation, and the stress response. My goal, as principal investigator and mentor of a diverse team of graduate and undergraduate students, is to develop interventions to improve pain management and reduce human suffering.

Research Interests

Pain and Pain Management
Opioid and Cannabinoid Systems
Chronic Disease
Immunology
Pharmacology

Selected Publications

*graduate mentee; **undergraduate mentee

Trexler*, KR, Vanegas*, SO, Poklis, JL, & Kinsey, SG (2020). The synthetic cannabinoid AB-FUBINACA induces physical withdrawal in mice. Drug and Alcohol Dependence. In press.

Gross*, JD, White, AN, Kaski*, SW, Trexler* KR, Wix, KA, Rodriguiz, RM, Wetsel, WC, Kinsey, SG, Siderovski, DP, Setola, V. (2020). Genetic deletion of Rgs12 in mice affects serotonin transporter expression and function in vivo and ex vivo. Journal of Psychopharmacology. In press.

Eckard*, ML, Trexler*, KR, Anderson, KG, & Kinsey, SG (2020). Precipitated Δ9-THC withdrawal reduces motivation for sucrose reinforcement in mice. Pharmacology, Biochemistry, and Behavior. In press.

Trexler*, K.R., Eckard*, M.L., and Kinsey, S.G. (2019). CB1 positive allosteric modulation attenuates Δ9-THC withdrawal and NSAID-induced gastric inflammation. Pharmacology, Biochemistry, and Behavior. 177:27-33

Trexler*, R., Nass*, S.R., Crowe*, M.S., Jones**, M.S., McKitrick**, A.W., Gross, J., Siderovski, D.P., & Kinsey, S.G. (2018). Novel tests of spontaneous and precipitated THC withdrawal in mice. Drug and Alcohol Dependence. 191:14-24.

Neeley, B; Overholt**, T; Artz, E, Kinsey, SG, & Marsat, (2018). Selective and context-dependent social and behavioral effects of cannabinoids in Ghost Knifefish. Brain Behavior and Evolution. 91(4):214-227.

Crowe*, M.S., Wilson, C.D., Leishman, E., Banks, M., Bradshaw, H.B., Prather, P.L., & Kinsey, S.G. (2018). The monoacylglycerol lipase inhibitor KML29 synergistically potentiates the analgesic effects of gabapentin in mice. British Journal of Pharmacology. 174(23):4523-4539.

Donvito, G., Nass*, SR, Wilkerson, JL, Curry, Z., Schurman, LD, Kinsey, SG, & Lichtman, AH. (2018). The endogenous cannabinoid system: a budding source of targets for treating inflammatory and neuropathic pain. 43(1):52-79.

Crowe*, M.S. & Kinsey, S.G. (2017). MAGL inhibition modulates gastric secretion and motility following NSAID exposure in mice. European Journal of Pharmacology. 807:198-204.

Wilkerson, JL, Ghosh, S, Bagdas, D, Mason, BL, Crowe*, MS, Hsu, K, Wise, LE, Kinsey, SG, Damaj, MI, Cravatt, BF and Lichtman, AH. (2016). Diacylglycerol lipase beta inhibition reverses nociceptive behavior in mouse models of inflammatory and neuropathic pain. British Journal of Pharmacology. 173(10):1678-92.

McBean*, A.L., Kinsey, S.G., Montgomery-Downs, H.M. (2016). Effects of a Single Night of Postpartum Sleep on Childless Women's Daytime Functioning. Physiology & Behavior. 156:137-47.

Ignatowska-Jankowska, B.M., Bailie, G., Crowe*, M.S., Kinsey, S.G., Ross, R., & Lichtman, A.H. (2015). A Cannabinoid CB1 Receptor Positive Allosteric Modulator Reduces Neuropathic Pain in the Mouse with no Psychoactive Effects. 40(13):2948-59.

Ghosh, S., Kinsey, S.G., Liu, Q., Hruba, L, McMahon, L.R., Wise, L.E., Abdullah, R.A., Selley, D.E., Sim- Selley, L.J., Cravatt, B.F., & Lichtman, A.H. (2015). Full FAAH inhibition combined with partial monoacylglycerol lipase inhibition: Augmented and sustained antinociceptive effects with negligible cannabimimetic side effects in mice. Journal of Pharmacology and Experimental Therapeutics. 354:111-120.

Nass*, S.R., Long, J.Z., Schlosburg, J.E., Cravatt, B.F., Lichtman, A.H., & Kinsey, S.G. (2015) Endocannabinoid catabolic enzymes function to maintain thermal homeostasis in response to environmental or immunological challenge. Journal of Neuroimmune Pharmacology. 10:364-370.

Crowe*, M.S., Leishman, E., Gujjar, R., Mahadevan, A., Banks, M.L., Bradshaw, H.B., & Kinsey, S.G. (2015) Dual Cyclooxygenase and Monoacylglycerol Lipase Inhibition Synergistically Attenuates Neuropathic Pain. British Journal of Pharmacology. 172:1700-1712.

Grim, T.W., Ghosh, S., Hsu, K, Cravatt, B.F., Kinsey, S.G., & Lichtman, A.H. (2014). Co-administration of a FAAH inhibitor and an NSAID produces enhanced anti-allodynic effects in murine neuropathic and inflammatory pain models. Pharmacology, Biochemistry, and Behavior. 124:405-411.

Crowe*, M.S., Nass*, S.R., Gabella*, K.M., and Kinsey, S.G. (2014). The endocannabinoid system modulates stress, emotionality, and inflammation. Brain, Behavior, and Immunity. 42:1-5.

Honors & Awards

Eberly College Outstanding Researcher Award, West Virginia University, 2019

Postdoctoral Best Abstract Award, American Society for Pharmacology and Experimental Therapeutics, 2011

Trainee Scholarship, Psychoneuroimmunology Research Society, 2010

Scientific Achievement Award, International Cannabinoid Research Society, 2008

Meritorious Teaching Award, The Ohio State University, 2007